Commercially Available Complement Component-Depleted Sera Are Unexpectedly Codepleted of Ficolin-2
نویسندگان
چکیده
منابع مشابه
Ficolin-2 inhibitors are present in sera after prolonged storage at −80 °C
Ficolins can activate the lectin pathway of the complement system that provides innate immune protection against pathogens, marks host cellular debris for clearance, and promotes inflammation. Baseline inflammation increases with aging in a phenomenon known as "inflammaging." Although IL-6 and C-reactive protein are known to increase with age, contributions of many complement factors, including...
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ژورنال
عنوان ژورنال: Clinical and Vaccine Immunology
سال: 2014
ISSN: 1556-6811,1556-679X
DOI: 10.1128/cvi.00370-14